Isaiah 53:5

But he was wounded for our transgressions, he was bruised for our iniquities: the chastisement of our peace was upon him; and with his stripes we are healed.

But he was wounded - a bodily wound: not mere mental sorrow; mªcholaal (H2490), from chaalal (H2490) - literally pierced; minutely appropriate to Messiah, whose hands, feet, and side were pierced (Psalms 22:16). Margin, wrongly, from a Hebrew root, chuwl (H2342), to writhe, translates, 'tormented.'

For our transgressions ... for our iniquities (Rom. 4:28; 2 Corinthians 5:21; Hebrews 9:28; 1 Peter 3:18) - the cause for which He suffered, not His own, but our sins.

He was bruised - with crushing inward and outward suffering (note, Isaiah 53:10).

The chastisement of our peace, [Hebrew, muwcar (H4148); the Septuagint, paideia (G3809)] - literally, the correction inflicted by a parent on children for their good (Hebrews 12:5; Hebrews 12:10). Not punishment strictly, so far as He individually was concerned; for this can take place only where there is guilt, which He did not have; but, He took on Himself the chastisement whereby the peace (reconciliation with our Father; Romans 5:1; Ephesians 2:14; Ephesians 2:17) of those who were already in the divine purpose the children of God was to be effected (Hebrews 2:14).

Was upon him - as a burden: parallel to "hath borne" and "carried."

With his stripes - minutely prophetic of His being scourged (Matthew 27:26; 1 Peter 2:24).

We are healed - spiritually (Psalms 41:4; Jeremiah 8:22). As "griefs," the term for mental ailments, is used of bodily ailments, Isaiah 53:4, so conversely, "healed," the term for bodily cure, is here used of the cure of the sold.