Genesis 19:7

and said, I pray you, brethren, do not so wickedly. This was the consequence of Lot's having settled in the midst of a godless and wicked people. Lot, having gone out and locked the door behind him in order to protect his guests, confronted a mob that had gone crazy with unnatural lust. His plea, in which he addressed them as brethren and begged them not to act in such a wicked manner, fell on deaf ears.