Genesis 48:1

And it came to pass after these things that one told Joseph, the news was brought him by a special messenger, Behold, thy father is sick. This was not long after Jacob had made arrangements for the transfer of his body to Canaan for burial. And he (Joseph) took with him his two sons, Manasseh and Ephraim, who were now about twenty years old; Manasseh may have been about twenty-four and Ephraim a few years younger.