Mark 3:21

And when His friends heard of it, they went out to lay hold on Him; for they said, He is beside Himself.

No sooner had Jesus returned to the city and to the house, no sooner had He come home, than a crowd again assembled. So urgent were they in their demand to see Him that Christ and His disciples were not even given time to partake of the necessary food needed to sustain life. If the eagerness of these people had only been for the Bread of Life, if they had only been hungering and thirsting after righteousness, there would not be a discordant element in the entire story. But their object was more than ever a glimpse of the great Healer and Benefactor; His message interested them little or not at all. In the meantime those nearest to the Lord, His relatives, His mother and His brothers, who are mentioned also at the end of the chapter, were becoming worried about Him. They had heard about the multitudes and their intense insistence upon seeing Jesus and giving Him no rest. So they set out from where they were with the purpose of taking Him under their care; for they had gained the impression, and no longer made any effort to conceal it, that He was in an unhealthy state of excitement, due to overwork, bordering on insanity. This peculiar idea, which was not at all flattering to the Lord, was due to lack of proper knowledge as to His power. Jesus was the Son of God, and He might become tired and weak, but He would not submit to the extent as was supposed by His relatives.