Numbers 12:10

And the cloud departed from off the Tabernacle, it mounted aloft, in token of the fact that the relations between God and His people were severed; and, behold, Miriam became leprous, white as snow; instead of being acknowledged by God as a leader of the people by the side of Moses, she was cursed with the plague, which would exclude her from the midst of the congregation as an unclean person, an outcast; and Aaron looked upon Miriam, and, behold, she was leprous; her whole body was seized with the terrible sickness in a moment of time.