1 Samuel 6:4

What shall be the trespass-offering? they desire particular information, because they were ignorant of the nature and manner of the worship of Israel's God, and they might easily understand that there were some kinds of offerings which God would not accept. Golden emerods, i.e. figures of that part of the body which was the seat of the disease, which by its swelling, or some other way, represented also the disease itself; which they offered not in contempt of God, for they sought to gain his favour hereby; but in testimony of their humiliation, that by leaving this monument of their own shame and misery they might obtain pity from God, and freedom from their disease. Golden mice; which marred their land, (as it. is related, 1 Samuel 6:5) by destroying the fruits thereof; as the other plague afflicted their bodies.