And I beheld when he had opened the sixth seal; the sixth of those seals with which the book was sealed, mentioned Revelation 5:1: this signifieth the revelation of some things which should happen in some certain period of time, but what period is the question, as to which interpreters differ. Some think, the time when Jerusalem was taken; but this was a time past twenty-six or twenty-seven years before John was in Patmos, where he had this vision about things that shall be, Revelation 1:1, Revelation 22:6. Some think, that period of time which shall be immediately before the day of judgment; but that guess seemeth worse, for after this there was a seventh seal to be opened. Some think, the period of the church's conflict with antichrist. But Mr. Mede's judgment (followed by many other famous men) seems best, that it denotes that period when Constantine, the first Christian emperor, restored peace to the church, by overturning the whole pagan state, and making Christianity the religion of the greatest part of the world. This was about the year 311, and perfected upon his victory over Licinius, 325. In this I acquiesce. Let us now see how what is said in this and the following verses about this period will agree to that time. And, lo, there was a great earthquake: the great question is here, what is meant by this great earthquake, the darkening of the sun, the moon becoming as blood, &c. No history recording any such prodigies, hath made many (taking these things in the natural, literal sense) to say the period under the first seal signifies either the time when Jerusalem was taken, or the day of judgment; but there is a metaphorical sense of these expressions, very usual in the prophetical writings, to show great changes in states; and in this sense it is to be taken here. Thus the prophet describeth the great change God would make in Jerusalem, Isaiah 29:6, Thou shalt be visited of the Lord of hosts with thunder, and with earthquake, and great noise, with storm and tempest, and the flame of devouring fire: and Jeremiah 15:9, Her sun is gone down whlie it was yet day. And, Ezekiel 32:7, the change God would work in the ruin of Egypt, is thus expressed: When I shall put thee out, I will cover the heaven, and make the stars thereof dark; and the moon shall not give her light. All the bright lights of heaven will I make dark over thee. So Joel 2:10,31, and Joel 3:15. What is an earthquake, but the shaking of the earth? And under this notion God expresseth the changes he makes in states and kingdoms, Isaiah 2:19,21 Isaiah 24:18 Haggai 2:6,7. Thus by earthquake here is to be understood a great change in the Roman empire. And the sun became black as sackcloth of hair, and the moon became as blood: the sun signifies those that are in the highest power; the moon, those that are next to them in place and dignity.

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