Jeremiah 21:6

Jeremiah goes on with the same discourse, even that God had resolved to destroy Jerusalem and the people, at least for a time. But he points out here what he intended to do, even that he would consume them by pestilence and famine, as long as they continued in the city; as though he had said, “Though these Chaldeans may not immediately take the city by means of a siege, yet its destruction shall be worse, for famine shall rage within and consume them.” We now perceive the design of the Prophet.

But we must keep in mind what I reminded you of yesterday, — that God assumes to himself what might have been ascribed to the Chaldeans, for he makes himself the author of all these calamities; I will smite, he says, the inhabitants of this city, both man and beast; by a great pestilence shall they die This was the first kind of punishment; before the enemy rushed into the city the pestilence had consumed many of the people. Now there is a circumstance mentioned which shews how dreadful would be their state, for not only men would perish, but even brute animals. It was no wonder that God’s vengeance extended to horses, and oxen, and asses; for we know that all these were created for the use of man. Hence when God manifested his wrath as to these animals, His object was to fill men with greater terrors; for they thus saw oxen and asses, though innocent, involved in the same punishment with themselves. For how can we suppose that horses and asses deserved to perish by diseases, or through want of daily food? But God sets forth such a spectacle as this, that he may more effectually touch men; for they thus see that the whole world is exposed to a curse through their sins. They are indeed constrained to know how great their sinfulness is; for on this account it is that the earth becomes dry and barren, that the elements above and below perform not their offices, so that the sterility of the ground deprives animals of their food, and the infection of the air kills them. But on this subject we have spoken elsewhere.