Psalms 4:2

2.O ye sons of men. The happy result of the prayer of David was, that resuming courage, he was able not only to repel the fury of his enemies, but also to challenge them on his part, and fearlessly to despise all their machinations. That our confidence, therefore, may remain unshaken, we ought not, when assailed by the wicked, to enter into conflict without being furnished like David with the same armor. The sum is, that since God was determined to defend David by his own power, it was in vain for all the men in the world to endeavor to destroy him; however great the power which they otherwise might have of doing him injury. By calling those whom he addresses the sons, not of Adam, or of some common persons but of men, he seems by the way to reprove their pride. (52) I do not agree with certain Jewish expositors who think that nobles or men of rank are meant. It is rather an ironical concession of what they claimed to themselves, by which he ridicules their presumption, in esteeming themselves to be noble and wise, whereas it was only blind rage which impelled them to wicked enterprises. In the words how long, he condemns their perverse obstinacy; for what he means, is not that they were stirred up against him merely by some sudden impulses, but that the stubborn purpose of injuring him was deeply fixed in their hearts. Had not their maliciousness deprived them of their understanding, the many instances in which God had proved himself to be David’s defender would have compelled them to desist from their attempts against him. But as they were fully determined to disgrace him whom God had exalted to the royal throne he asks them, How long they will persevere in their endeavors to turn his glory into shame And it is to be observed that although loaded with every kind of reproach, both among the high and the low he yet courageously keeps fast hold of the glory or the honor of royalty which God had graciously promised him, or had conferred upon him, and is fully persuaded that God will at length vindicate his right to it, however much his enemies might wickedly endeavor to blot and obscure it by treating his pretensions with derision and scorn.

How long will ye love vanity? In these words, he partly reproaches his enemies for the wicked and perverse passions with which he saw them to be impelled, although they falsely pretended to be actuated by a godly zeal; and he partly derides their folly in flattering themselves with the hope of success while fighting against God. And it is a most pointed rebuke. Even when the ungodly rush headlong into all manner of wickedness with the grossest (53) malice, they soothe themselves with deceitful flatteries in order not to be disturbed with the feelings of remorse. David, therefore, cries out, that wilfully to shut their eyes and varnish their unrighteousness with deceitful colors, would avail them nothing. The ungodly may indeed flatter and delude themselves, but when they are brought in good earnest to the trial, it will be always manifest that the reason why they are deceived is, because from the beginning they were determined to deal deceitfully. Now, from this place, we ought to take a shield of invincible steadfastness as often as we see ourselves overmatched in prudence and subtlety by the wicked. For with whatever engines they assault us, yet if we have the testimony of a good conscience, God will remain on our side, and against him they shall not prevail. They may greatly excel in ingenuity, and possess much power of hurting us, and have their plans and subsidiary aid in the greatest readiness, and be very shrewd in discernment, yet whatever they may invent, it will be but lying and vanity.