Genesis 3:15

Gen. 3:15. "I will put enmity between thee and the woman, and between thy seed and her seed: it shall bruise thy head, and thou shalt bruise his heel." Here the pronoun "he," the verb "bruise," and the affix "his" are all of the singular number, as Bedford observes in p. 166 of his "Scripture Chronology," (As before under Genesis 2:3) which shows that by "seed" is meant a particular person, and not her posterity in general; which observation is agreeable to that which the apostle Paul makes (Galatians 3:16), referring to what is said in Genesis 22:17; Genesis 22:18, where the singular pronoun or affix "his," and the singular verb "possess," is in like manner used when speaking of that "seed of Abraham," who should "possess the gate of his enemies," and "in whom all the families of the earth should be blessed." Bedford in his "Scripture Chronology" says the Jewish Paraphrasts express this text thus: "There shall be a remedy to mankind: but there shall be no remedy to thee the serpent. But there shall be a remedy to them in the latter age of the world, even in the days of King Messiah, who shall remember what thou didst in the beginning of the world;" and says, that Maimonides, a learned Jew, justly admires [= wonders] that the seed of the woman should be only mentioned, and not of Adam, without whom she could have no seed, and which must therefore be his seed; and that it should be said of " her seed," not of "his," that it bruised the serpent's head. "This," saith he, "is one of the passages in Scripture which is most wonderful, and not to be understood according to the letter, but contains great wisdom in it." In the old Creation, the woman was taken out of the man; in the new Creation, the man is taken out of the woman. God in the new creation honors the inferior; as man, the inferior nature, is honored above the angels.

Gen. 3:20