Psalms 40:14

Let them be ashamed and confounded together - See at Psalms 35:4, note; Psalms 35:26, note. This may be understood here rather as a confident expectation than a wish or desire. It implies the certainty that they would thus be ashamed and confounded; that is, that they would not be successful, or would be foiled in their purposes. But understood as a wish or prayer, it could not be improper. There is no sin in the wish that the wicked may not be successful in their plans, and may not be suffered to injure us. As the language of the Messiah it was in every way an appropriate prayer that the purposes of those who would defeat his design in coming into the world might be foiled - for on the execution of that design depended the salvation of a lost race.

That seek after my soul to destroy it - That seek after my life; that would destroy me. That is, they seek to kill me; they would take my life before the full time is come. As understood of the Messiah, this would refer to the times when his life was in danger, as it often was, before the full period had arrived for him to die: John 7:6; Matthew 26:18. The purpose of his enemies was to take his life; to prevent the spread of his doctrines; to cheek him in his work. The taking of his life at any time before the full period had arrived, or in any other way than that in which he had purposed to lay it down, would have been a defeat of his work, since in the plan of salvation it was contemplated that he should die at a certain time, and in a certain manner - that he should die at the time which had been predicted by the prophets, and in such a mode as to make an atonement for sin. All this would have been defeated if, before that time came, he had been put to death by stoning, or in any of the numerous ways in which his life was threatened.

Let them be driven backward, and put to shame, that wish me evil - Turned backward, as they are who are unsuccessful, or are defeated. Compare John 18:6.