Acts 18:23. And after he had spent some time there. Many expositors suppose that during this residence of St. Paul at Antioch took place his famous interview with the leading apostle of the circumcision, on which occasion Paul, to use his own words, withstood Peter to the face, because he was to be blamed (see Galatians 2:11 and following verses).

He departed on his third great missionary journey, about A.D. 54. He probably went first from Syrian Antioch to Tarsus, and then in a north-west direction through Galatia; and then turning south-west, he journeyed through Phrygia and so to Ephesus, where for a long period he took up his abode.

Strengthening all the disciples. That is, in the various churches founded by him and his companions during the first two missionary journeys. Many things alluded to in the Galatian epistle, written sometime in the Ephesian residence which immediately succeeded this long journey, were suggested by notes made during this visit.

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Old Testament