Rufus] cp. Mark 15:21. St. Mark probably wrote his Gospel at Rome.

Mine] i.e. St. Paul felt for her the affection of a son.

17-20. Warning against false teachers, probably Judaistic, whose doctrines St. Paul has dealt with in the Epistle. They may not have appeared at Rome as yet: cp. Philippians 1:15; (written from Rome).

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