John Gill's Exposition of the Whole Bible
Isaiah 5:13
Therefore my people are gone into captivity,.... Or rather, as Kimchi explains it, "shall go into captivity"; the past for the future; for this cannot be understood even of the captivity of the ten tribes, for they were not carried captive until the sixth year of Hezekiah's reign, 2 Kings 17:6 whereas this prophecy was delivered out many years before, even in the time of Uzziah, as is manifest from the following chapter, Isaiah 6:1 and much less it cannot design the captivity of Judah, but respects the captivity by the Romans, in future time.
Because [they have] no knowledge; of the work of the Lord, and the operations of his hands; the Septuagint and Arabic versions render it, "because they knew not the Lord", the Lord Jesus Christ, the Lord of glory, the true Messiah; they knew not his person, office, grace, and Gospel; they did not own and acknowledge him, but despised and rejected him; their ignorance was affected and voluntary; they had the means of knowledge, but did not make use of them; they would not know him, they would not attend to the strong and clear evidence of his being the Messiah, which prophecies, miracles, and his doctrines, gave of him; the things belonging to their peace they knew not, these were righteously hid from them, and hence destruction came upon them,
Luke 19:42 the words may be rendered in connection with the former, "therefore my people shall go into captivity without knowledge" b, unawares, unthought of, and unexpected; and the Jews, to the last; did not think their city would be taken, but that in some way of other salvation and deliverance would be wrought for them:
and their honourable men [are] famished, and their multitude dried up with thirst; or "shall be"; this is expressive of a famine of bread and water, which all, both high and low, prince and people, should be affected with; see Isaiah 3:1 and was true not only when Jerusalem was besieged by the Chaldeans, Jeremiah 52:6 Jeremiah 5:10 but when it was besieged by the Romans, in which the rich suffered as well as the poor; and was so great, that even women ate their own children, as Josephus c relates: this is threatened as a punishment of their rioting and drunkenness, Isaiah 5:11.
b לכן גלה עמי מבלי דעת "idcirco exsulat populus meus absque scientia", Cocceius; so Montanus. c De Bello Jud. l. 5. c. 10. sect. 2. 3. 12. 3. 6. 3, sect. 3.