[As] with a sword in my bones, mine enemies reproach me,.... The reproaches of his enemies were grievous and cutting to him, as if a sword pierced through the marrow in his bones, which, being very sensitive, gives exquisite pain. There is a various reading here: some copies, as Vatablus observes, read ב, "in", or with, and others כ, "as", which seems to be the truest; and our translators supply "as", to make the sense, though they read "with"; but some n only read "as"; and the sense is, the reproaches cast upon the psalmist were as a sword cutting and killing; and these reproaches were as follow;

while they say daily unto me, where [is] thy God?

Psalms 42:3.

n כרצח ως σφαγην, Symmachus in Drusius; "ut occisio", Pagninus, Amama; so Aben Ezra interprets it.

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